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Microbium. Thus, both genes were present in very early actinobacteria, but each gene has been lost many times in the later evolution of the phylum. These losses may conceivably have contributed to the evolution of branches such as Micrococcineae (Node 4 of Fig. 2) and Corynebacterineae (a sub-branch from node 6). The BldD regulon has been subjected to detailed analysis by immunoprecipitation of in
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Microbium. Thus, both genes were present in very early actinobacteria, but each gene has been lost many times in the later evolution of the phylum. These losses may conceivably have contributed to the evolution of branches such as Micrococcineae (Node 4 of Fig. 2) and Corynebacterineae (a sub-branch from node 6). The BldD regulon has been subjected to detailed analysis by immunoprecipitation of in
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On of genes for morphological differentiation and antibiotic production during vegetative growth and connecting the regulons of other regulators of these processes (den Hengst et al., 2010). BldD orthologues in simpler actinomycetes might well have roles both during growth, to repress functions associated with entry into stationary phase, and in stationary phase, in coordinating the expression of
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Pressed by BldD. Based on a consensus sequence derived from these ChIP-chip data, BldD recognition?2013 The Author. FEMS Microbiology Reviews published by John Wiley Sons Ltd on behalf of the Federation of European Microbiological SocietiesG. Chandra K.F. Chatersequences were found upstream of many of the same genes not only in other streptomycetes, but also in other sporulating actinobacteria
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Ed as a generator of endogenous NO that brings about the closure of stomata (Desikan et al., 2002), and nitrate and nitrite reductases generate NO in bacteria (Corker Poole, 2003; Vine et al., 2011). Like the binding of NO by nitrobindin (Bianchetti et al., 2010), these reactions are anoxic. This may explain why the WhiB7 (=WblC)-dependent response of M. tuberculosis to antibiotics was surprisin
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Microbium. Thus, both genes were present in very early actinobacteria, but each gene has been lost many times in the later evolution of the phylum. These losses may conceivably have contributed to the evolution of branches such as Micrococcineae (Node 4 of Fig. 2) and Corynebacterineae (a sub-branch from node 6). The BldD regulon has been subjected to detailed analysis by immunoprecipitation of in
1
Microbium. Thus, both genes were present in very early actinobacteria, but each gene has been lost many times in the later evolution of the phylum. These losses may conceivably have contributed to the evolution of branches such as Micrococcineae (Node 4 of Fig. 2) and Corynebacterineae (a sub-branch from node 6). The BldD regulon has been subjected to detailed analysis by immunoprecipitation of in
1
Sually taken only when all other solutions fail (Narula et al., 2012). Likewise, in streptomycetes, it seems that many (but not all) of the bld gene products, which are nearly all regulatory, feed in information relevant to this drastic decision and ensure that the whi gene cascade operates only under fully appropriate circumstances. The most ubiquitous bld genes are bldC, encoding an apparently s